Exploring new research avenues for osteoarthritis and rheumatoid arthritis in palaeopathology : interdisciplinary approaches focusing on methodological techniques
This project sought to examine and critically evaluate current methodologies for the analysis and interpretation of osteoarthritis and rheumatoid arthritis within palaeopathology, with reference to clinical research. A compartmental recording method was developed for osteoarthritis and a distinction between degenerative joint changes and osteoarthritis was maintained. This method was applied to the analysis of five Post-Medieval skeletal populations from both rural and urban sites from northern England. An analysis of the pattern and distribution of osteoarthritis and DJC between the sites, including rural versus urban differences, age and sex-specific comparisons, and, where possible, a comparison with contemporaneous sites from southern England was undertaken. A set of diagnostic criteria for rheumatoid arthritis was developed, applied, and tested on potential cases of rheumatoid arthritis within the archaeological record. Given this conditionâs scarcity within the palaeopathological context, a wider geographical and temporal analysis was conducted. Results, based on clinical research and differential prevalence rates, indicated that DJC and osteoarthritis should be assessed separately. General rural-urban
Craps, Davina Denise
Exploring new research avenues for osteoarthritis and rheumatoid arthritis in palaeopathology : interdisciplinary approaches focusing on methodological techniques. This project sought to examine and critically evaluate current methodologies for the analysis and interpretation of osteoarthritis and rheumatoid arthritis within palaeopathology, with reference to clinical research. A compartmental recording method was developed for osteoarthritis and a distinction between degenerative joint changes and osteoarthritis was maintained. This method was applied to the analysis of five Post-Medieval skeletal populations from both rural and urban sites from northern England. An analysis of the pattern and distribution of osteoarthritis and DJC between the sites, including rural versus urban differences, age and sex-specific comparisons, and, where possible, a comparison with contemporaneous sites from southern England was undertaken. A set of diagnostic criteria for rheumatoid arthritis was developed, applied, and tested on potential cases of rheumatoid arthritis within the archaeological record. Given this conditionâs scarcity within the palaeopathological context, a wider geographical and temporal analysis was conducted. Results, based on clinical research and differential prevalence rates, indicated that DJC and osteoarthritis should be assessed separately. General rural-urban
exploring new avenue osteoarthritis palaeopathology interdisciplinary approach focus methodological technique project_seek examine critically_evaluate current methodology analysis_interpretation osteoarthritis within palaeopathology reference clinical research record method_develop osteoarthritis distinction degenerative joint change osteoarthritis maintain method_apply analysis post_medieval skeletal_population rural_urban site_northern england analysis pattern_distribution osteoarthritis site_include rural versus urban difference age_sex specific comparison possible comparison contemporaneous site_southern england undertaken set diagnostic criterion develop_apply test_potential case within archaeological_record given condition scarcity within palaeopathological context_wider geographical_temporal analysis_conduct base clinical differential prevalence_rate indicate osteoarthritis assess separately general rural_urban