A history of embryonic stem cell research : concepts, laboratory work, and contexts
This thesis focuses on the history of embryonic stem cell research, spanning in particular the nineteenth and twentieth centuries. As yet, there has not been a comprehensive history of embryonic stem cell research carried out, which is a particular aim of this thesis. The first two chapters consider the conceptualisation of the stem cell, and the development and diversity of relevant disciplines and their establishment in the twentieth century; in particular, this covers heredity, genetics,embryology and development. This is illustrated through the use of experimental embryology, or âfantastical experimentsâ, that were proposed in the nineteenth century, and carried out in the twentieth. The third chapter considers the theoretical and practical links between cancer and embryonic cells. The fourth and fifth chapters explore the isolation and culture of murine and human embryonic stem cells, focusing on the social, political, and economic factors affecting stem cell research, and the motivations behind the isolation of embryonic stem cells in the 1980s and 1990s. The sixth chapter queries whether the history presented suggests that a new stem cell concept is emerging. There are three questions that this
Lancaster, Cheryl
A history of embryonic stem cell research : concepts, laboratory work, and contexts. This thesis focuses on the history of embryonic stem cell research, spanning in particular the nineteenth and twentieth centuries. As yet, there has not been a comprehensive history of embryonic stem cell research carried out, which is a particular aim of this thesis. The first two chapters consider the conceptualisation of the stem cell, and the development and diversity of relevant disciplines and their establishment in the twentieth century; in particular, this covers heredity, genetics,embryology and development. This is illustrated through the use of experimental embryology, or âfantastical experimentsâ, that were proposed in the nineteenth century, and carried out in the twentieth. The third chapter considers the theoretical and practical links between cancer and embryonic cells. The fourth and fifth chapters explore the isolation and culture of murine and human embryonic stem cells, focusing on the social, political, and economic factors affecting stem cell research, and the motivations behind the isolation of embryonic stem cells in the 1980s and 1990s. The sixth chapter queries whether the history presented suggests that a new stem cell concept is emerging. There are three questions that this
history stem cell concept laboratory work context focus history stem cell span particular yet comprehensive history stem cell carry particular aim thesis first_two consider conceptualisation stem cell development diversity relevant discipline establishment particular cover genetics development illustrate use experimental propose carry twentieth third_considers theoretical_practical link cell explore isolation culture human stem cell focus social_political economic_factor affect stem cell motivation_behind isolation stem cell sixth query whether history present suggest new stem cell concept emerge question